Liztox 100U + Saline 20ml

Liztox 100U

Liztox is a highly purified Clostridium type A botulinum toxin for the correction and prevention of expression lines. Due to the suppression of signaling between muscles and motor nerves, the product acts as a muscle relaxant and is used to combat dynamic wrinkles.

Application area:

• Correction of mimic wrinkles on the forehead, in the area between the eyebrows and in the décolleté area
• Hyperhidrosis treatment
• Restoration of a smooth skin surface
• Blepharospasm correction

Liztox Administration Protocol:

Supplies Needed:

• Liztox botulinum toxin 100U vial
• 1 mL syringes with 20 gauge needles (for drawing up) and 30G 0.5-inch needles (for injecting). Insulin syringes with attached 31G needles are also suitable.
• 0.9% sodium chloride (saline), preferably bacteriostatic/preserved
• Alcohol pads
• Gauze
• Ice packs
• Topical anesthetic (optional)
• Marker/pencil (optional)
• Sharps container

Injection Preparation:

• Sanitize hands and don medical gloves.
• Extract the Liztox vial from its packaging.
• Remove the plastic cap, leaving the metal ring intact.
• Use an alcohol pad to clean the rubber stopper of the Liztox vial.
• For a 100U vial, draw up 2.0 ml of room-temperature sterile saline into the syringe. For a 50U vial, draw up 1.0 ml. The saline may be drawn into one or two 1.0 ml syringes, or a larger syringe can be used, ensuring the correct volume of saline for dilution.
• Insert the needle into the center of the Liztox vial's rubber stopper and gently press the syringe plunger to add the saline. Repeat with additional syringes if necessary, or use the same syringe to add a total of 2.0 ml of sterile saline.
• Discard needles in a sharps container.
• Swirl the Liztox vial gently to mix. Avoid shaking.
• Let the prepared Liztox sit for 5 minutes while preparing for the treatment.
• Use a 30 or 31G 0.5-inch needle for injections.

Procedure Technique:

• Follow general cleansing and makeup removal for the treatment area.
• Mark injection sites as required.
• Customize injections based on individual patient assessments.
• Adhere to treatment plans for specific muscle groups.

Treatment of Frown Lines (Glabellar Lines):

• Identify target muscles: procerus and corrugators.
• Use dynamic assessment to tailor injections.
• Inject deeply at bony origin of medial corrugator, keeping lateral injections superficial.
• Injection points should stay close to the brow to avoid eyelid ptosis.
• Avoid diffusion to lower frontalis fibers by keeping corrugator injection points close to the brow.

Treatment of Crow’s Feet Lines (CFLs):

• Identify target muscle: lateral orbicularis oculi.
• Individualize injection pattern based on CFL distribution.
• Use intradermal injections to reach the muscle without increasing bruising risk.
• Carefully inject below the lateral canthus in patients with eyelid issues.
• Avoid injecting into zygomatic muscles to preserve smile.

Forehead Lines:

• Identify target muscles: frontalis.
• Use dynamic assessment to determine injection points.
• Inject subdermally to minimize bleeding.
• Place injection points at least 2 cm above the brows.
• Tailor doses and patterns to individual forehead height and muscle localization.

Brow Lift:

• Inject superficially below the brow for lateral elevation.
• Avoid impairing lower frontalis action.

Lower Eyelid Injections:

• Assess lower eyelid tone.
• Perform single intradermal injection lateral to mid-pupillary line, 4–5 mm below lid margin.

Bunny Lines:

• Identify target muscle: transverse nasalis.
• Perform single intradermal injection in bunny-line area.
• Avoid lateral injection to prevent smile alteration.

Elevation of Nasal Tip:

• Identify target muscle: depressor septi nasi.
• Perform single subdermal injection at base of columella for correct indication.

Correction of Gummy Smile:

• Perform chemomodulation of upper-lip elevators for mild to moderate cases.
• Assess carefully and document preexisting asymmetries.
• Perform treatment in two sessions, addressing upper-lip elevators and depressor septi nasi.

Perioral Wrinkles (“Barcode” Lines):

• Perform four superficial dermal injections per side.
• Use caution in patient selection and dose determination.
• Consider association with hyaluronic acid for optimal results.

Step 3: Post-Injection Care

• Potential complications include bruising, ptosis, and asymmetry.
• Techniques to reduce bruising include avoiding superficial blood vessels and applying pressure and ice post-injection.
• Post-procedure precautions include avoiding sleeping face down, bending over, and vigorous exercise.

Ingredient: Botulinum toxin type A, human serum albumin 0.5 mg, sodium chloride 0.9 mg.

Composition: 100 units

Storage: The unopened lyophilized vial should be stored in a refrigerator (2C - 8C).

Shelf Life: 24 months from manufacturing date